From Megan Von Isenburg, DUH Medical Librarian:

Don’t forget to check Custom ID for the Duke guidelines. You can get to it from Clinical Tools, Virtual PIN, or by typing Custom ID into the URL bar. Here’s a direct link – http://customid.duhs.duke.edu/DukeMed/DUH/Index.asp

To find the best evidence/literature –

Be sure not to search for just c diff. It doesn’t map to the official heading clostridium difficile, and you miss most articles. Remember, you can always check details to determine if you found articles with the right heading.
For articles on a specific drug, a simple clostridium difficile AND cholestyramine or clostridium difficile AND fidaxomicin or even clostridium difficile AND fecal transplantwill pull up articles on those specific drugs.
If you don’t want to commit to a management strategy yet, but want to find any good evidence for treatment of refractory c diff, you need to consider the various ways authors might say refractory. Something like clostridium difficile AND (refractory OR failure OR resistant) might do the trick well enough – then just click on Therapy/Treatment to see RCTs or Systematic Reviews to see SRs and meta-analyses.
Similarly, articles on recurrent c diff would be found here – clostridium difficile AND (recurrent OR recurrence)

Management of C Diff

Any feedback to our teams working on huddles and localization can be submitted here.